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DIABETES DISCOVERY: PROTEIN PATHWAY POINTS TO POSSIBLE TREATMENT




Scientists have discovered that one of the most diabolical proteins implicated in diabetes not only kills insulin-producing cells through one mechanism, but also damages the cells it doesn't kill through a second, novel mechanism. Reigning in this rogue protein, called TXNIP, could significantly control diabetes, a disease that affects nearly 9 percent of Americans and is rapidly becoming a major cause of death and disability worldwide. The scientists, from the University of Alabama at Birmingham, identified several never-before-realized routes to target TXNIP with drugs.


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